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過(guò)氧化物酶體增殖物激活受體γ輔激活因子1α(PPARgC1a)單克隆抗體

Monoclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a)

LEM6; PGC-1(alpha); PGC-1v; PGC1; PGC1A; PPARGC1; Ligand effect modulator 6

  • 過(guò)氧化物酶體增殖物激活受體γ輔激活因子1α(PPARgC1a)單克隆抗體 產(chǎn)品包裝(模擬)
  • 過(guò)氧化物酶體增殖物激活受體γ輔激活因子1α(PPARgC1a)單克隆抗體 產(chǎn)品包裝(模擬)
  • Certificate 通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對(duì)PPARgC1a的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別PPARgC1a。

用法

免疫印跡：0.2-2μg/mL;1:500-5000
免疫組織化學(xué)：5-20μg/mL;1:50-200
免疫細(xì)胞化學(xué)：5-20μg/mL;1:50-200
最佳稀釋倍數(shù)最終由用戶(hù)決定。

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

參考文獻(xiàn)

雜志 參考文獻(xiàn)
Coronary Artery Disease Impaired myocardium energetics associated with the risk for new-onset atrial fibrillation after isolated coronary artery bypass graft surgery [Pubmed: 24463787]
Molecular and cellular biochemistry Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension [Pubmed: 23099843]
Diabetes. Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway [Pubmed:25249574]
Psychoneuroendocrinology Maternal stress predicts altered biogenesis and the profile of mitochondrial proteins in the frontal cortex and hippocampus of adult offspring rats [PubMed: 26143539]
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry The level of circulating PGC1α in cardiovascular diseases [Article: 10.1134]
Neuroscience Letters Unlike PPARgamma, neither other PPARs nor PGC-1alpha is elevated in the cerebrospinal fluid of patients with multiple sclerosis [pubmed:28483651]
The American Journal of the Medical Sciences Serum peroxisome proliferator-activated receptor gamma coactivator-1α related to myocardial energy expenditure in patients with chronic heart failure [Doi: 10.1016/j.amjms.2018.12.002]
Brain Research The effect of antecedent-conditioning high-intensity interval training on BDNF regulation through PGC-1α pathway following cerebral ischemia [Pubmed: 31866362]
Food & Function Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise [Pubmed: 32797125]
Brown and beige adipose tissue regulate systemic metabolism to resist diet-induced obesity through metabolite signals in an inter-organ signaling axis []
CLINICAL NUTRITION Long lasting protective EFFECTS of early L-ARGININE TREAMENT on ENDOTHELIUM in an in Vitro STUDY [33743287]
Nature Communications Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis [33772024]
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